USC-OGP 2-DE database Two-dimensional polyacrylamide gel electrophoresis database

USC-OGP 2-DE database  Search by                Maps             Select Remote Interfaces [All Interfaces] SWISS-2DPAGE World-2DPAGE Portal World-2DPAGE Repository Exclude local DBs has only effect if a remote interface is selected

Searching in 'USC-OGP 2-DE database' for entry matching: Q9NW31 USC-OGP 2-DE database:  Q9NW31 Q9NW31 General information about the entry View entry in simple text format Entry name CSN4_HUMAN Primary accession number Q9NW31 integrated into USC-OGP 2-DE database on  January 17, 2017 (release 1) 2D Annotations were last modified on January 17, 2017 (version 1) General Annotations were last modified on  April 5, 2017 (version 2) Name and origin of the protein Description RecName: Full=COP9 signalosome complex subunit 4; Short=SGN4; Short=Signalosome subunit 4; AltName: Full=JAB1-containing signalosome subunit 4;. Gene name Name=COPS4 Synonyms=CSN4 Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION Author 1., Author 2. Submitted (Mar-2011) to Current 2D PAGE maps for identified proteins How to interpret a protein PLATELET_4-7 {PLATELET 4-7} Homo sapiens (Human)   map experimental info   PLATELET_4-7 MAP LOCATIONS: SPOT OGP-0423: pI=5.42; Mw=41108 PLATELET_5-6 {PLATELET 5-6} Homo sapiens (Human)   map experimental info   PLATELET_5-6 MAP LOCATIONS: SPOT OGP-0707: pI=5.43; Mw=42795 Cross-references UniProtKB/Swiss-Prot Q9BT78; CSN4_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name CSN4_HUMAN Primary accession number Q9BT78 Secondary accession number(s) B3KN88 B3KST5 Q561W7 Q9NW31 Q9Y677 Sequence was last modified on  June 1, 2001 (version 1) Annotations were last modified on  March 15, 2017 (version 141) Name and origin of the protein Description RecName: Full=COP9 signalosome complex subunit 4; Short=SGN4; Short=Signalosome subunit 4; AltName: Full=JAB1-containing signalosome subunit 4; Gene name Name=COPS4 Synonyms=CSN4 Encoded on Name=COPS4; Synonyms=CSN4 Keywords 3D-structure; Acetylation; Alternative splicing; Cell junction; Complete proteome; Cytoplasm; Cytoplasmic vesicle; Direct protein sequencing; Nucleus; Reference proteome; Signalosome; Synapse. Copyright Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL AF100757; AAD43021.1; -; mRNA EMBL AK001210; BAA91555.1; -; mRNA EMBL AK024005; BAG51250.1; -; mRNA EMBL AK094238; BAG52847.1; -; mRNA EMBL AC021105; -; NOT_ANNOTATED_CDS; Genomic_DNA EMBL AC073840; -; NOT_ANNOTATED_CDS; Genomic_DNA EMBL AC108473; -; NOT_ANNOTATED_CDS; Genomic_DNA EMBL CH471057; EAX05921.1; -; Genomic_DNA EMBL CH471057; EAX05922.1; -; Genomic_DNA EMBL BC004302; AAH04302.1; -; mRNA EMBL BC009292; AAH09292.1; -; mRNA EMBL BC093007; AAH93007.1; -; mRNA CCDS CCDS3600.1; -. [Q9BT78-1]; . CCDS CCDS58909.1; -. [Q9BT78-2]; . RefSeq NP_001244935.1; NM_001258006.1. [Q9BT78-2]; . RefSeq NP_001317656.1; NM_001330727.1; . RefSeq NP_057213.2; NM_016129.2. [Q9BT78-1]; . UniGene Hs.190384; -; . PDB 4D0P; X-ray; 1.60 A; A=1-363 PDB 4D10; X-ray; 3.80 A; D/L=1-406 PDB 4D18; X-ray; 4.08 A; D/L=1-406 PDB 4WSN; X-ray; 5.50 A; D/L/T/b/j/r=1-406 PDBsum 4D0P; -; . PDBsum 4D10; -; . PDBsum 4D18; -; . PDBsum 4WSN; -; . ProteinModelPortal Q9BT78; -; . SMR Q9BT78; -; . BioGrid 119324; 97; . DIP DIP-34516N; -; . IntAct Q9BT78; 31; . MINT MINT-1464138; -; . STRING 9606.ENSP00000264389; -; . iPTMnet Q9BT78; -; . PhosphoSitePlus Q9BT78; -; . SwissPalm Q9BT78; -; . BioMuta COPS4; -; . DMDM 55976582; -; . OGP Q9BT78; -; . REPRODUCTION-2DPAGE IPI00171844; -; . EPD Q9BT78; -; . MaxQB Q9BT78; -; . PaxDb Q9BT78; -; . PeptideAtlas Q9BT78; -; . PRIDE Q9BT78; -; . Ensembl ENST00000264389; ENSP00000264389; ENSG00000138663. [Q9BT78-1]; . Ensembl ENST00000509093; ENSP00000425976; ENSG00000138663. [Q9BT78-2]; . GeneID 51138; -; . KEGG hsa:51138; -; . UCSC uc003hoa.4; human. [Q9BT78-1]; . CTD 51138; -; . DisGeNET 51138; -; . GeneCards COPS4; -; . HGNC HGNC:16702; COPS4; . HPA HPA036894; -; . HPA HPA042828; -; . MIM 616008; gene; . neXtProt NX_Q9BT78; -; . OpenTargets ENSG00000138663; -; . PharmGKB PA26756; -; . eggNOG KOG1497; Eukaryota; . eggNOG ENOG410XPDE; LUCA; . GeneTree ENSGT00730000111161; -; . HOGENOM HOG000158382; -; . HOVERGEN HBG051136; -; . InParanoid Q9BT78; -; . KO K12178; -; . PhylomeDB Q9BT78; -; . TreeFam TF101147; -; . Reactome R-HSA-5696394; DNA Damage Recognition in GG-NER; . Reactome R-HSA-6781823; Formation of TC-NER Pre-Incision Complex; . Reactome R-HSA-8856825; Cargo recognition for clathrin-mediated endocytosis; . ChiTaRS COPS4; human; . GeneWiki COPS4; -; . GenomeRNAi 51138; -; . PRO PR:Q9BT78; -; . Proteomes UP000005640; Chromosome 4; . Bgee ENSG00000138663; -; . CleanEx HS_COPS4; -; . ExpressionAtlas Q9BT78; baseline and differential; . Genevisible Q9BT78; HS; . GO GO:0030054; C:cell junction; IDA:HPA; . GO GO:0008180; C:COP9 signalosome; IDA:UniProtKB; . GO GO:0005829; C:cytosol; IBA:GO_Central; . GO GO:0070062; C:extracellular exosome; IDA:UniProtKB; . GO GO:0016607; C:nuclear speck; IDA:HPA; . GO GO:0005654; C:nucleoplasm; TAS:Reactome; . GO GO:0005634; C:nucleus; IDA:UniProtKB; . GO GO:0008021; C:synaptic vesicle; IDA:UniProtKB; . GO GO:0019784; F:NEDD8-specific protease activity; TAS:Reactome; . GO GO:0000715; P:nucleotide-excision repair; DNA damage recognition; TAS:Reactome GO GO:0000338; P:protein deneddylation; IDA:UniProtKB; . GO GO:0006283; P:transcription-coupled nucleotide-excision repair; TAS:Reactome; . Gene3D 1.10.10.10; -; 1; . InterPro IPR000717; PCI_dom; . InterPro IPR011991; WHTH_DNA-bd_dom; . Pfam PF01399; PCI; 1; . SMART SM00088; PINT; 1; . SUPFAM SSF46785; SSF46785; 1; .

Gateways to other related servers

• The World-2DPAGE Constellation - Entry point to the world-wide 2-DPAGE resources.
• World-2DPAGE Repository - A public repository for gel-based proteomics data linked to protein identification published in the literature.
• World-2DPAGE Portal - A dynamic portal to query simultaneously world-wide gel-based proteomics databases.
• SWISS-2DPAGE - The Geneva Two-dimensional polyacrylamide gel electrophoresis database.
• ExPASy - The resources web server of the Swiss Institute of Bioinformatics

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